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骨髓增生异常综合征——随访20年及以上患者的转归

Myelodysplastics--fate of those followed for twenty years or more.

作者信息

Barden G A, Meyer L C, Stelling F H

出版信息

J Bone Joint Surg Am. 1975 Jul;57(5):643-7.

PMID:1097448
Abstract

Of a total of 143 myelodysplastic patients treated between 1928 and 1951, there were sixty-three patients with severe myelodysplasia whose records allowed long-term review. At the time of writing twenty-nine were alive and were twenty to forty-three years old. All were walking in the hospital while under an intensive physical therapy program. However only two of the nine with twelfth thoracic-second lumbar function were walking at final follow-up as adults, while nineteen of the twenty with function at the third lumbar level were doing so. The status of the hips did not correlate with the ability to walk. One-third of the survivors were self-supporting at the time of writing. About one-half had scoliosis and in one-third was greater than 20 degrees.

摘要

在1928年至1951年间接受治疗的143例骨髓发育异常患者中,有63例患有严重骨髓发育异常,其病历可供长期复查。在撰写本文时,29例患者存活,年龄在20至43岁之间。在强化物理治疗方案下,所有患者都能在医院行走。然而,在最终随访时,作为成年人,第九胸椎至第二腰椎功能患者中只有2例能够行走,而第三腰椎水平有功能的20例患者中有19例能够行走。髋关节状况与行走能力无关。在撰写本文时,三分之一的幸存者能够自理。约一半患者有脊柱侧弯,其中三分之一侧弯大于20度。

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引用本文的文献

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Surgical Management of Hip Problems in Myelomeningocele: A Review Article.脊髓脊膜膨出中髋关节问题的外科治疗:一篇综述文章。
Arch Bone Jt Surg. 2016 Jun;4(3):197-203.
2
Upper and lower urinary tract outcomes in adult myelomeningocele patients: a systematic review.成人脊髓脊膜膨出患者的上下尿路结局:系统评价。
PLoS One. 2012;7(10):e48399. doi: 10.1371/journal.pone.0048399. Epub 2012 Oct 31.
3
Orthopedic management of spina bifida. Part I: hip, knee, and rotational deformities.脊柱裂的骨科治疗。第一部分:髋、膝及旋转畸形。
J Child Orthop. 2009 Dec;3(6):441-9. doi: 10.1007/s11832-009-0214-5. Epub 2009 Oct 25.
4
The operative treatment of spinal deformities in MMC.脊髓脊膜膨出中脊柱畸形的手术治疗
Neurosurg Rev. 1993;16(1):45-52. doi: 10.1007/BF00308613.
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Development of scoliosis in myelomeningocele. Differences in the history caused by idiopathic pattern.脊髓脊膜膨出患者脊柱侧弯的发展。特发性模式导致的病史差异。
Neurosurg Rev. 1993;16(4):301-6. doi: 10.1007/BF00383841.