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[喉癌患者细胞核形态计量分析及区域淋巴结状况]

[Morphometric analysis of cell nuclei and regional lymph node status with patients suffering from laryngeal carcinoma].

作者信息

Dobroś W, Gil K, Ryś J, Stanisz-Wallis K

机构信息

Oddział Otolaryngologii Szpitala Wojewódzkiego w Tarnowie.

出版信息

Otolaryngol Pol. 2000;54 Suppl 31:164-6.

Abstract

We analysed 61 patients suffering from squamous cell carcinoma of larynx, who were treated in the Department of Otolaryngology, Collegium Medicum, Jagiellonian University, Cracow. Seven parameters of the cell nuclei and their variance were studied with the aid of a computer-assisted system of image analysis. The slides were viewed with a high-resolution black and white camera (Mintron) connected to the computer with the frame graber card (512 x 512 pixels with 256 gray levels, Vist software) at x630 magnification with an Axiophot microscope. It was established that high values of nuclear area, perimeter, density, long or shot nuclear axis carry an increased risk of metastases to regional lymph nodes.

摘要

我们分析了61例喉鳞状细胞癌患者,这些患者均在克拉科夫雅盖隆大学医学院耳鼻喉科接受治疗。借助计算机辅助图像分析系统研究了细胞核的七个参数及其方差。使用连接到计算机的高分辨率黑白相机(Mintron),通过帧捕捉卡(512×512像素,256级灰度,Vist软件),在Axiovert显微镜下以630倍放大倍数观察载玻片。结果表明,细胞核面积、周长、密度、长短轴数值较高时,区域淋巴结转移风险增加。

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