Resuscitation. 2000 Aug 23;46(1-3):261-6. doi: 10.1016/s0300-9572(00)00287-2.
Use of standard ACLS protocols for all patients who are critically poisoned may not result in an optimal outcome. Care of severely poisoned patients can be enhanced by urgent consultation with a medical toxicologist. Alternative approaches required in severely poisoned patients include: o Higher doses than usual. o Drugs that are rarely used to treat cardiac arrest (amrinone, calcium, esmolol, glucagon, insulin, labetalol, phenylephrine, physostigmine, and sodium bicarbonate). o Heroic measures, such as prolonged CPR and use of circulatory assist devices. When resuscitation is unsuccessful, organ donation may still be an option.
对所有中毒严重的患者使用标准的高级心血管生命支持(ACLS)方案可能无法取得最佳疗效。通过紧急咨询医学毒理学家可加强对严重中毒患者的护理。严重中毒患者所需的替代方法包括:o 比通常剂量更高。o 很少用于治疗心脏骤停的药物(氨力农、钙剂、艾司洛尔、胰高血糖素、胰岛素、拉贝洛尔、去氧肾上腺素、毒扁豆碱和碳酸氢钠)。o 积极措施,如延长心肺复苏(CPR)时间和使用循环辅助设备。当复苏失败时,器官捐献仍可能是一种选择。