Suppr超能文献

颅后窝脑膜孤立性纤维瘤:磁共振成像与组织学相关性——病例报告

Solitary fibrous tumor of the meninges in the posterior cranial fossa: magnetic resonance imaging and histological correlation--case report.

作者信息

Nawashiro H, Nagakawa S, Osada H, Katoh H, Ohnuki A, Tsuzuki N, Miyazawa T, Shima K, Ogata S, Aida S

机构信息

Department of Neurosurgery, National Defense Medical College, Saitama.

出版信息

Neurol Med Chir (Tokyo). 2000 Aug;40(8):432-4. doi: 10.2176/nmc.40.432.

Abstract

A 58-year-old female presented with a rare case of intracranial solitary fibrous tumor (SFT) manifesting as progressive ataxic gait and hearing loss on the left persisting for 6 months with recent symptoms of increased intracranial pressure. Computed tomography demonstrated a large isodense irregular-shaped mass in the left posterior cranial fossa. T2-weighted magnetic resonance imaging showed two components appearing as very low intensity and high intensity. Extreme-lateral suboccipital craniotomy was performed. Gross total resection was achieved except for some dural attachment in the jugular foramen. All symptoms and signs subsided after surgery. Histological, immunohistochemical, and electron microscopic examinations led to a diagnosis of SFT. The strongly hypointense areas on the T2-weighted images were hypocellular region characterized by disorganized spindle cells and thick bands of collagen. The hyperintense areas on the T2-weighted images were hypercellular region mimicking hemangiopericytoma. Strong immunoreactivity for CD34 was also helpful in the diagnosis. Electron microscopy revealed absence of pinocytic vesicles and dense laminae which are characteristic of hemangiopericytoma. The magnetic resonance imaging appearance of SFT seems to be pathognomonic.

摘要

一名58岁女性,患有罕见的颅内孤立性纤维瘤(SFT),表现为进行性共济失调步态和左侧听力丧失6个月,近期出现颅内压升高症状。计算机断层扫描显示左侧后颅窝有一个大的等密度不规则形肿块。T2加权磁共振成像显示有两个成分,分别表现为极低信号强度和高信号强度。进行了枕下极外侧开颅手术。除颈静脉孔处一些硬脑膜附着外,实现了肿瘤全切。术后所有症状和体征均消退。组织学、免疫组织化学和电子显微镜检查确诊为SFT。T2加权图像上的强低信号区为细胞减少区,其特征是梭形细胞排列紊乱和厚的胶原带。T2加权图像上的高信号区为细胞增多区,类似血管外皮细胞瘤。CD34的强免疫反应性也有助于诊断。电子显微镜显示缺乏血管外皮细胞瘤特征性的吞饮小泡和致密板层。SFT的磁共振成像表现似乎具有诊断特异性。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验