Slucky-Shraga I, Wolk M, Volis S, Vulikh I, Sompolinsky D
Dept. of Medicine and Microbiology Laboratory, Mayanei Hayeshua Hospital, Bnei Brak.
Harefuah. 2000 Jul;139(1-2):25-9, 79.
We examined all ceftriaxone-resistant Escherichia coli isolates obtained from clinical samples during 16 months (1 Dec. '97-31 Mar. '99). A total of 97 resistant isolates from 36 patients were obtained, mostly from urine specimens. Of these patients, 35/36 were over 75 years old, most lived in nursing homes, were dependent on nursing in their daily lives, and were incontinent and/or had indwelling catheters. All 97 isolates had similar susceptibility profiles: resistant to ciprofloxacin, gentamicin, ampicillin, amoxycillin/clavulanate, tricarcillin/clavulanate, aztreonam, and cefuroxime; decreased susceptibility to ceftazidime and cefepime; and susceptible to imipenem and meropenem. Double-disc tests indicated that all strains produced extended spectrum beta-lactamase(s). All the isolates belonged to 1 of 3 E. coli serotypes: 79 were 0153:H31, 13 were 0142:H10, and 5 were 0102:H6.
我们检查了在16个月期间（1997年12月1日至1999年3月31日）从临床样本中分离出的所有耐头孢曲松大肠杆菌菌株。共从36名患者中获得了97株耐药菌株，大部分来自尿液标本。在这些患者中，35/36名年龄超过75岁，大多数居住在养老院，日常生活依赖护理，并且大小便失禁和/或留置导尿管。所有97株菌株具有相似的药敏谱：对环丙沙星、庆大霉素、氨苄西林、阿莫西林/克拉维酸、替卡西林/克拉维酸、氨曲南和头孢呋辛耐药；对头孢他啶和头孢吡肟敏感性降低；对亚胺培南和美罗培南敏感。双纸片试验表明所有菌株均产生超广谱β-内酰胺酶。所有分离株属于3种大肠杆菌血清型之一：79株为O153:H31，13株为O142:H10，5株为O102:H6。
