Kaliman P A, Samokhin A A, Samokhina L M
Kharkov State University.
Ukr Biokhim Zh (1999). 2000 Jan-Feb;72(1):89-92.
Mechanisms of proteinase-inhibitor proteinase system response was estimated following of cobalt chloride injection. The increase proteinase activity, which led to significant decrease of alpha-2-macroglobulin (alpha-2-MG) level was established that indicated to the removal of the proteinase in complex with alpha-2-MG from the organism. Increase of alpha-1-proteinase inhibitor (alpha-1-PI) trypsin-inhibitory activity in the kidneys testify about removal of oxidative alpha-1-PI.
在注射氯化钴后评估蛋白酶 - 抑制剂蛋白酶系统的反应机制。确定蛋白酶活性增加，这导致α - 2 - 巨球蛋白（α - 2 - MG）水平显著降低，表明与α - 2 - MG结合的蛋白酶从体内被清除。肾脏中α - 1 - 蛋白酶抑制剂（α - 1 - PI）胰蛋白酶抑制活性的增加证明了氧化型α - 1 - PI的清除。
