Safarov M I
A. I. Karayev Institute of Physiology, Azerbaijan Academia of Sciences, Baku.
Ukr Biokhim Zh (1999). 2000 Mar-Apr;72(2):77-81.
The impact of benzene vapor (0.35 mg/l) of low concentration on the contents of free GABA, Glu and Asp, as well as on the enzyme activities of GDC and GABA-T in mitochondrial fractions of different brain regions of adult male rats was investigated. The conclusion was put forward that GABA increase by means of "keeping" inhibition provided for nerve cells defense from extremal excitation, taking place under the chronic exposure to the benzene low concentration.
研究了低浓度苯蒸气（0.35毫克/升）对成年雄性大鼠不同脑区线粒体部分中游离γ-氨基丁酸（GABA）、谷氨酸（Glu）和天冬氨酸（Asp）含量以及谷氨酸脱羧酶（GDC）和γ-氨基丁酸转氨酶（GABA-T）酶活性的影响。得出的结论是，在长期暴露于低浓度苯的情况下，通过“保持”抑制作用使GABA增加，为神经细胞抵御极端兴奋提供保护。
