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[使用替溴芬预防流感的经验]

[Experience in the use of Tebrophen for influenza prevention].

作者信息

Stel'makh S G, Levchenko I F

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1975 Jun(6):113-5.

PMID:1098334
Abstract

The efficacy of influenca prophylaxis by a new Soviet chemopreparation tebrophen was studied during the influenza epidemics of 1972-1973 caused by the influenza virus of A/Hong-kong/68 and A/England/72/H3N2/types. Investigations were carried out under conditions of an epidemiological experience among the organized (adult) collective bodies (4352 persons in all). The preparation was instilled intranasally in the form of a 0.25 and 1% ointment on vaseline base. The efficacy index was 2.0-2.7, and the protection index--51--60%.

摘要

在由A/香港/68和A/英格兰/72/H3N2型流感病毒引起的1972 - 1973年流感流行期间,对苏联一种新的化学预防药物特布芬预防流感的效果进行了研究。研究是在有组织的(成人)集体机构(共4352人)的流行病学试验条件下进行的。该制剂以0.25%和1%凡士林基质软膏的形式经鼻内滴注。疗效指数为2.0 - 2.7,保护指数为51% - 60%。

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