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膜增生性肾小球肾炎。从单纯型进展为新月体型,并在移植后复发。

Membranoproliferative glomerulonephritis. Progression from the pure form to the crescentic form with recurrence after transplantation.

作者信息

McCoy R, Clapp J, Seigler H F

出版信息

Am J Med. 1975 Aug;59(2):288-92. doi: 10.1016/0002-9343(75)90366-6.

Abstract

Described are the clinical course and renal morphologic findings in a patient with membranoproliferative glomerulonephritis. intially, the patient had a pure form of membranoproliferative glomerulonephritis but after a 3 year course, it became crescentic. After a renal allograft was performed, membranoproliferative glomerulonephritis recurred within 1 month in a pure form and subsequently developed into the crescentic form. This change occurred in the host kidney as well as in the allograft immediately after immunosuppressive and steroid therapy was discontinued.

摘要

描述了一名膜增生性肾小球肾炎患者的临床病程和肾脏形态学表现。最初,该患者患有单纯形式的膜增生性肾小球肾炎,但经过3年病程后,发展为新月体性。肾移植后,膜增生性肾小球肾炎在1个月内以单纯形式复发,随后发展为新月体性。在停用免疫抑制和类固醇治疗后,这种变化立即在宿主肾脏和移植肾中出现。

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