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三种低温固化骨水泥的蠕变特性:一项临床前评估

Creep properties of three low temperature-curing bone cements: a preclinical assessment.

作者信息

Verdonschot N, Huiskes R

机构信息

Orthpaedic Research Laboratory, University of Nijmegen, Nijmegen, The Netherlands.

出版信息

J Biomed Mater Res. 2000 Sep;53(5):498-504. doi: 10.1002/1097-4636(200009)53:5<498::aid-jbm8>3.0.co;2-h.

Abstract

The mechanical characteristics of new bone cements should be assessed before these cements are released on the orthopedic market in great quantities. In this study, we present the deformational response of 3 relatively new, low-curing temperature bone cements (Cemex RX, Cemex System, and Cemex Isoplastic) to a dynamic compressive force in comparison to Simplex P bone cement. For this purpose, dynamic compressive creep tests were performed on cylindrical shaped specimens at a maximal load level of 20 MPa for a period of 250,000 cycles. The results showed that Cemex System and Cemex RX produced creep rates that were higher (20% and 30%, respectively) as compared to Simplex P bone cement. The creep behavior of Cemex Isoplastic was very similar to that of Simplex P. It was concluded that although Cemex RX and Cemex System produced higher creep rates than Simplex P, these differences were not considered excessive. Hence, although other tests are required to assess the safety and efficacy of these new cements, the dynamic creep properties under compression can be considered adequate for clinical use.

摘要

在新型骨水泥大量投放骨科市场之前,应对其力学特性进行评估。在本研究中,我们展示了3种相对新型的、低固化温度骨水泥(Cemex RX、Cemex System和Cemex Isoplastic)与Simplex P骨水泥相比,在动态压缩力作用下的变形响应。为此,对圆柱形试件进行了动态压缩蠕变试验,最大载荷水平为20 MPa,持续250,000次循环。结果表明,与Simplex P骨水泥相比,Cemex System和Cemex RX产生的蠕变率更高(分别为20%和30%)。Cemex Isoplastic的蠕变行为与Simplex P非常相似。得出的结论是,尽管Cemex RX和Cemex System产生的蠕变率高于Simplex P,但这些差异并不被认为过大。因此,尽管需要其他测试来评估这些新型骨水泥的安全性和有效性,但压缩状态下的动态蠕变特性可被认为足以满足临床使用。

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