泌尿生殖系统横纹肌肉瘤。治疗选择。

Genitourinary rhabdomyosarcoma. Treatment options.

作者信息

Kaefer M, Rink R C

机构信息

Department of Pediatric Urology, James Whitcomb Riley Hospital for Children, Indiana University Medical Center, Indianapolis, USA.

出版信息

Urol Clin North Am. 2000 Aug;27(3):471-87. doi: 10.1016/s0094-0143(05)70095-1.

DOI:10.1016/s0094-0143(05)70095-1

PMID:10985147

Abstract

Dramatic improvements have occurred in the treatment and prognosis of the child with rhabdomyosarcoma over the past 2 decades. Increased understanding of tumor behavior has improved survival and focused attention on important quality of life issues. Future therapeutic advances will depend largely on an improved molecular understanding of altered cell behavior and the continued efforts of multi-institutional studies.

摘要

在过去20年里，横纹肌肉瘤患儿的治疗和预后有了显著改善。对肿瘤行为的进一步了解提高了生存率，并使人们将注意力集中在重要的生活质量问题上。未来治疗方面的进展将在很大程度上取决于对细胞行为改变的分子层面理解的提升以及多机构研究的持续努力。