First total synthesis of dragmacidin A via indolylglycines.
作者信息
Kawasaki T, Enoki H, Matsumura K, Ohyama M, Inagawa M, Sakamoto M
机构信息
Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo, 204-8588 Japan.
出版信息
Org Lett. 2000 Sep 21;2(19):3027-9. doi: 10.1021/ol006394g.
PMID:10986099
Abstract
The first total synthesis of dragmacidin A has been accomplished using condensation of two indolylglycines followed by cyclization and reduction. The general and practical method for synthesis of indolylglycines via Wittig reaction, azide addition, and reduction from indolin-3-ones is also described.
摘要
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