Efficient one-pot synthesis of indol-3-yl-glycines via uncatalyzed Friedel-Crafts reaction in water.
作者信息
Ghandi Mehdi, Taheri Abuzar
机构信息
School of Chemistry, University College of Science, University of Tehran, Tehran, Iran.
出版信息
Molecules. 2009 Mar 5;14(3):1056-61. doi: 10.3390/molecules14031056.
Abstract
The three component reaction of primary aliphatic amines, glyoxalic acid and indole or N-methylindole in water at ambient temperature affords indol-3-yl or N-methylindol-3-yl-glycine in almost quantitative yields.
摘要
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