Gusak P P
Arkh Anat Gistol Embriol. 1975 Jun;68(6):102-15.
The increased degree of death of cells due to increased functional stresses may serve as a starting factor responsible for the compensatory growth. This fact allows considering reparative regeneration and compensatory growth as phenomena of the same class. Different forms of reparative growth (intracellular regeneration and proliferation of cells, endomorphosis and epimorphosis) serve to concrete tasks of reparation at different levels of organization of the morphological substrate. They are sustained by endogeneous morphogenetical mechanisms developing independently of other levels and of environment. In the subsystem of lover levels of organization the involved morphogenetical mechanisms may sustain not only compensation of the lost structures but also their overproduction. As a rule the program of reparative processes may be realized on higher (e. g. organic) level but partly. Among available criteria of regeneration at the present time the calculation of mitoses should be considered the most adequate one. The systemic approach may prove to be a perspective method both for estimation of regeneratory effect and for deeper analysis of reparative phenomena in general.
由于功能压力增加导致的细胞死亡程度增加，可能是引发代偿性生长的起始因素。这一事实使得修复性再生和代偿性生长可被视为同一类现象。不同形式的修复性生长（细胞内再生和细胞增殖、内变形和外变形）服务于形态学基质不同组织水平上的具体修复任务。它们由独立于其他水平和环境而发展的内源性形态发生机制维持。在较低组织水平的子系统中，所涉及的形态发生机制不仅可以维持对丢失结构的补偿，还可以使其过度产生。通常，修复过程的程序可能在较高（例如器官）水平上部分实现。在目前可用的再生标准中，有丝分裂的计算应被认为是最适当的标准。系统方法可能被证明是一种有前景的方法，既可以用于评估再生效果，也可以用于总体上更深入地分析修复现象。
