Appleton C P, Firstenberg M S, Garcia M J, Thomas J D
Division of Cardiovascular Diseases, Mayo Clinic Scottsdale, Arizona, USA.
Cardiol Clin. 2000 Aug;18(3):513-46, ix. doi: 10.1016/s0733-8651(05)70159-4.
The role of left ventricular (LV) diastolic function in health and disease is still incompletely understood and under appreciated by most primary care physicians and many cardiologists. Physical examination, electrocardiogram, and chest radiographs are unreliable in making the diagnosis of LV diastolic dysfunction in most individuals, and invasive measurements of cardiac pressures, rates of LV relaxation, and LV compliance are costly, clinically impracticable as they carry increased risk, and require special catheters and software analysis programs. The authors address the definition of LV diastolic dysfunction, history of diastole, LV filling patterns, pulmonary venous flow velocity variables, additional ancillary data, practical echo-Doppler evaluation of LV diastolic function, and limitations.
左心室舒张功能在健康与疾病中的作用仍未被完全理解，大多数初级保健医生和许多心脏病专家对此也认识不足。在大多数个体中，体格检查、心电图和胸部X线片对于诊断左心室舒张功能障碍并不可靠，而侵入性测量心脏压力、左心室舒张速率和左心室顺应性成本高昂，在临床上不实用，因为它们会增加风险，并且需要特殊导管和软件分析程序。作者阐述了左心室舒张功能障碍的定义、舒张的历史、左心室充盈模式、肺静脉血流速度变量、其他辅助数据、左心室舒张功能的实用超声多普勒评估以及局限性。
