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梅尼埃病

Meniere's disease.

作者信息

Woodworth B A, Fitzpatrick P C, Gianoli G J

出版信息

J La State Med Soc. 2000 Jul;152(7):314-9.

Abstract

Meniere's disease is an idiopathic disorder of the inner ear characterized by the syndrome of endolymphatic hydrops, episodic vertigo, fluctuating hearing loss, tinnitus, and aural fullness. People with this disorder may be severely disabled. Medical therapy exists in the form of diuretics and dietary restriction of salt to minimize the fluid pressure in the labyrinth and cochlea. Treatment of allergies with desensitization and steroids has also shown to be effective in selected patients. Surgical therapies exist in two categories, conservative and ablative. Endolymphatic sac decompression with or without shunt placement remains highly effective and we feel that it should be the first line surgical therapy for patients who fail medical therapy. Ablative therapies include labyrinthectomy (medical or surgical) and vestibular neurectomy. Both of these procedures control the episodic vertigo by destroying vestibular function in the affected ear and should be reserved for patients who have persistent vertigo in spite of more conservative treatments.

摘要

梅尼埃病是一种特发性内耳疾病,其特征为内淋巴积水综合征、发作性眩晕、波动性听力损失、耳鸣和耳胀满感。患有这种疾病的人可能会严重致残。医学治疗方法包括使用利尿剂和限制饮食中的盐分,以尽量降低内耳迷路和耳蜗中的液体压力。采用脱敏和类固醇治疗过敏在部分患者中也显示出有效。手术治疗分为两类,即保守性手术和破坏性手术。无论是否放置分流管,内淋巴囊减压术仍然非常有效,我们认为对于药物治疗无效的患者,它应作为一线手术治疗方法。破坏性手术包括迷路切除术(药物或手术方式)和前庭神经切除术。这两种手术通过破坏患耳的前庭功能来控制发作性眩晕,应仅用于尽管接受了更保守治疗仍有持续性眩晕的患者。

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