Rigel D S, Carucci J A
Ronald O. Perelman Department of Dermatology, New York University Medical School, NY, USA.
CA Cancer J Clin. 2000 Jul-Aug;50(4):215-36; quiz 237-40. doi: 10.3322/canjclin.50.4.215.
Malignant melanoma continues to present a significant public health problem as its incidence is rising faster than that of any other cancer in the US. At current rates, 1 in 74 Americans will develop melanoma during his or her lifetime. Management of melanoma is a complex issue requiring a multidisciplinary approach. The most effective method of protection against the development of melanoma is minimization of ultraviolet exposure from sunlight. Early detection and treatment are critical and result in improved patient survival rates. Surgical excision remains the mainstay of treatment but many new promising therapies are being investigated. It is hoped that increased public and professional awareness and education in all areas relating to the prevention, detection, and treatment of malignant melanoma will contribute to decreasing trends in the incidence and mortality from this cancer in the future.
恶性黑色素瘤仍然是一个重大的公共卫生问题，因为在美国其发病率的上升速度比其他任何癌症都要快。按照目前的发病率，每74个美国人中就有1人在其一生中会患上黑色素瘤。黑色素瘤的治疗是一个复杂的问题，需要多学科方法。预防黑色素瘤发生的最有效方法是尽量减少阳光中的紫外线照射。早期发现和治疗至关重要，可提高患者生存率。手术切除仍然是主要的治疗方法，但许多新的有前景的疗法正在研究中。希望在与恶性黑色素瘤的预防、检测和治疗相关的所有领域提高公众和专业人士的认识及教育水平，将有助于在未来降低这种癌症的发病率和死亡率。
