Pancreatic cancer: state-of-the-art care.

This review focuses on the pathogenesis, diagnosis, staging, and treatment of pancreatic cancer. Although much is needed to improve the still dismal outlook for patients with this disease, significant progress has been made in its surgical and oncologic management. Furthermore, our deepening understanding of the molecular genetics of pancreatic cancer lends hope for the possibility of earlier detection, which would result in substantial improvements in survival.