Natural product derived inhibitors of lipoprotein associated phospholipase A2, synthesis and activity of analogues of SB-253514.
作者信息
Pinto I L, Boyd H F, Hickey D M
机构信息
SmithKline Beecham Pharmaceuticals, Harlow, Essex, UK.
出版信息
Bioorg Med Chem Lett. 2000 Sep 4;10(17):2015-7. doi: 10.1016/s0960-894x(00)00395-4.
Abstract
The synthesis of analogues of SB-253514, a novel natural product derived inhibitor of lipoprotein associated phospholipase A2 (Lp-PLA2), is described together with their ability to inhibit Lp-PLA2.
摘要
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