Peterman T A, Lin L S, Newman D R, Kamb M L, Bolan G, Zenilman J, Douglas J M, Rogers J, Malotte C K
National Center for STD, HIV, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Sex Transm Dis. 2000 Sep;27(8):446-51. doi: 10.1097/00007435-200009000-00004.
Many studies measure sex behavior to determine the efficacy of sexually transmitted disease (STD)/HIV prevention interventions.
To determine how well measured behavior reflects STD incidence.
Data from a trial (Project RESPECT) were analyzed to compare behavior and incidence of STD (gonorrhea, chlamydia, syphilis, HIV) during two 6-month intervals.
A total of 2879 persons had 5062 six-monthly STD exams and interviews; 8.9% had a new STD in 6 months. Incidence was associated with demographic factors but only slightly associated with number of partners and number of unprotected sex acts with occasional partners. Many behaviors had paradoxical associations with STD incidence. After combining behavior variables to compare persons with highest and lowest risk behaviors, the STD incidence ratio was only 1.7.
Behavioral interventions have prevented STD. We found people tend to have safe sex with risky partners and risky sex with safe partners. Therefore, it is difficult to extrapolate the disease prevention efficacy of an intervention from a measured effect on behavior alone.
许多研究通过测量性行为来确定性传播疾病（STD）/艾滋病病毒（HIV）预防干预措施的效果。
确定所测量的行为在多大程度上反映STD发病率。
对一项试验（尊重项目）的数据进行分析，以比较两个6个月期间的行为和STD（淋病、衣原体感染、梅毒、HIV）发病率。
共有2879人接受了5062次为期6个月的STD检查和访谈；8.9%的人在6个月内感染了新的STD。发病率与人口统计学因素有关，但与性伴侣数量以及与偶尔性伴侣发生无保护性行为的次数仅有轻微关联。许多行为与STD发病率存在矛盾的关联。在合并行为变量以比较风险行为最高和最低的人群后，STD发病率比仅为1.7。
行为干预预防了STD。我们发现人们倾向于与高风险伴侣进行安全性行为，而与低风险伴侣进行高风险行为。因此，仅根据对行为的测量效果来推断干预措施的疾病预防效果是困难的。
