Dodin G, Vandergheynst P, Levoir P, Cordier C, Marcourt L
ITODYS, associé au CNRS, Université Denis Diderot, Paris, France.
J Theor Biol. 2000 Oct 7;206(3):323-6. doi: 10.1006/jtbi.2000.2127.
A correlation function that compares each base in a DNA sequence to its various neighbours and which is subsequently processed by Fourier and wavelet transforms has been developed. The procedure has been applied to sequences from the human chromosome 22, to nef genes from various HIV clones and to myosin heavy chain DNA. It permits to readily visualize regular features in DNA which are related to the stability of heteroduplexes formed upon strand slippage.
已开发出一种相关函数，该函数将DNA序列中的每个碱基与其各种相邻碱基进行比较，随后通过傅里叶变换和小波变换进行处理。该程序已应用于人类22号染色体的序列、各种HIV克隆的nef基因以及肌球蛋白重链DNA。它能够轻松地可视化DNA中与链滑动时形成的异源双链体稳定性相关的规则特征。
