生长抑素对血管加压素诱导的水流动的拮抗作用。
Antagonism of vasopressin-induced water flow by somatostatin.
作者信息
Strandhoy J W, Zook T E
出版信息
Res Commun Chem Pathol Pharmacol. 1979 Jun;24(3):599-602.
PMID:109904
Abstract
The ability of somatostatin to modify the water premeability of the toad bladder was examined. Somatostatin had a small effect on basal water flow and antagonized the hydrosmotic effect of vasopressin. Water flow induced by cyclic AMP was enhanced. These results may explain the diuretic and hyposthenuric effects of somatostatin in vivo.
摘要
研究了生长抑素调节蟾蜍膀胱水通透性的能力。生长抑素对基础水流量有轻微影响，并拮抗血管加压素的渗透作用。由环磷酸腺苷诱导的水流量增加。这些结果可能解释了生长抑素在体内的利尿和低渗尿作用。
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