Derganc M
Scand J Plast Reconstr Surg. 1979;13(1):195-200. doi: 10.3109/02844317909013056.
In adults supplemental parenteral nutrition (PN) is advisable in burns over 40% especially when weight loss exceeds 10% of body weight. In children with smaller reserves and higher requirement of proteins and energy no rigid scheme for parenteral supplementation is used at our unit. In a young infant it may be added already at a 20-30% deep burn, especially with connected gastrointestinal tract problems, infection etc. Metabolic and protein requirements are estimated 50-100% in addition to their normal needs. Hypertonic glucose (gradually increased from 20-40%), covered with insulin in the early phase, is used as source of carbohydrates. L-amino acid mixture containing the "pediatric essential amino acids" histidine and cysteine is given as a nitrogen source. 20% Intralipid is given in a gradually increased amount of 2-4 g/kg per day to provide calories and essential fatty acids. Among electrolytes K, Ca, P and Mg must be added. Increased amounts of vitamin C and folate are needed by burned children. Vitamin E is also required during prolonged lipid administration. Trace elements (Zn. Fe, etc.) are supplied orally or i.v. with special solutions or fresh plasma infusions. Our experience with parenteral nutrition in severely burned children will be presented. There were no severe metabolic side-effects but sepsis represented the major problem. The concomitant heat preservation by warming the room and use of infra-red heaters is emphasized.
对于成人,烧伤面积超过40%时,尤其是体重减轻超过体重的10%,建议补充肠外营养(PN)。对于储备较少、蛋白质和能量需求较高的儿童,我们单位没有采用严格的肠外补充方案。对于幼儿,在深度烧伤达20 - 30%时,尤其是伴有胃肠道问题、感染等情况时,可能就需要补充肠外营养。除正常需求外,代谢和蛋白质需求估计要增加50 - 100%。高渗葡萄糖(从20 - 40%逐渐增加)在早期用胰岛素覆盖,用作碳水化合物来源。给予含“小儿必需氨基酸”组氨酸和半胱氨酸的L - 氨基酸混合物作为氮源。每天按2 - 4 g/kg的量逐渐增加给予20%的英脱利匹特,以提供热量和必需脂肪酸。电解质中必须添加钾、钙、磷和镁。烧伤儿童需要增加维生素C和叶酸的量。在长期给予脂质期间也需要维生素E。微量元素(锌、铁等)通过口服或静脉注射特殊溶液或输注新鲜血浆来补充。将介绍我们在严重烧伤儿童中应用肠外营养的经验。没有严重的代谢副作用,但脓毒症是主要问题。强调通过提高房间温度和使用红外线加热器来进行伴随的保温。