Nodiff E A, Saggiomo A J, Tanabe K, Chen E H, Shinbo M, Tyagi M P, Kozuka A, Otomasu H, Verma B L, Goff D
J Med Chem. 1975 Oct;18(10):1011-9. doi: 10.1021/jm00244a012.
A series of new 9-phenanthrene amino alcohols has been prepared in which each compound bears from one to five halogen or halogen-containing moieties. A number of these compounds are extremely active against Plasmodium berghei in the mouse. Some structural requirements for optimal efficacy are considered.
