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[二氧化碳激光声带切除术:形态功能结果分析]

[CO2 laser cordectomy: analysis of morpho-functional results].

作者信息

Iengo M, Villari P, Masula I, De Clemente M

机构信息

Università di Catanzaro, Clinica ORL.

出版信息

Acta Otorhinolaryngol Ital. 2000 Apr;20(2):106-20.

PMID:10992603
Abstract

The authors have conducted a study of a large sampling of subjects who had undergone different types of cordectomy. The purpose of this study has been to analyze the anatomo-functional variables encountered with such procedures. In particular, the following were studied: post-surgical vocal recovery; type of glottic sphincter scarring, particularly as related to the extent of surgical excision; effect commissure synecchia has on the post-operative voice, again related to type of exeresis; different types of functional compensation related to the various surgical excisions and means by which the new scarring cord is built; severity of dysphonia resulting after each type of surgery. The study involved 69 patients who had undergone different types of cordectomy: from limited procedures--the so-called submucosal cordectomies for circumscribed, superficial neoplasms--to more radical ones, performed on tumours extending to the laryngeal ventricle of one or both sides. A history was taken of all the cases and they underwent videolaryngoscopy, psychoacoustic evaluation and voice spectrography. This study revealed the following: vocal recovery is achieved within 1-3 months after surgery, particularly when the exeresis was limited; longer recovery times were required for more radical surgery; with horizontal exeresis the prognosis for sphincteric recovery--characterized by a good neocord--is better than with procedures removing structures on the vertical plane (true vocal cord + ventricle + false cord) where scarring generally proves inadequate to re-establish a satisfactory sphincter; commissure synecchia is unusual in all types of surgery and is more frequent in bilateral forms. This is not specifically responsible for aggravating the dysphonia although, except in a few cases, it can make an important contribution in limiting the glottic opening and facilitating vocal sounds; as regards functional compensation, the observations show that the larynx is able to adapt to anatomic damage, the entire organ playing a part in reducing the air space to create a more or less valid phonatory sphincter, each part in its own way. Among the most noteworthy mechanisms for functional compensation we find the cord-neocord, the glottic mechanism at the false cords and ary-arythenoid compensation. There is no direct relationship between phonatory mode and neocord conformation since not all cases achieving a satisfactory neocord actually use glottic phonation. Although the Yanagihara spectrographic classification of dysphonia cannot distinguish between severe dysphonia and aphonia, it can be applied in the objective classification of limited post-cordectomy vocal compromise. In fact, spectrography is able to document that: Type II dysphonia--light--is unusual and was only found in 2 cases with a excellent neocord and a perfect pneumo-phonic picture; Type II dysphonia--moderate--is most often found in submucosal cordectomies and in other cases of monolateral exeresis with adequate scarring; Type IV dysphonia actually corresponds to the most important forms. It is present in all types of cordectomy and is most prevalent in those with a severe adductor deficit associated with inadequate or poorly balanced supraglottic functional compensation.

摘要

作者对大量接受不同类型声带切除术的受试者进行了一项研究。本研究的目的是分析此类手术中遇到的解剖功能变量。具体而言,研究了以下内容:术后声音恢复情况;声门括约肌瘢痕形成的类型,特别是与手术切除范围相关的类型;声带粘连对术后声音的影响,同样与切除类型相关;与各种手术切除相关的不同类型的功能代偿以及新瘢痕形成声带的构建方式;每种手术类型后导致的发音困难的严重程度。该研究涉及69例接受不同类型声带切除术的患者:从有限的手术——即所谓的针对局限性浅表肿瘤的黏膜下声带切除术——到更彻底的手术,后者针对延伸至一侧或双侧喉室的肿瘤。记录了所有病例的病史,并对他们进行了电子喉镜检查、心理声学评估和嗓音频谱分析。本研究揭示了以下情况:术后1 - 3个月内可实现声音恢复,特别是当切除范围有限时;更彻底的手术需要更长的恢复时间;水平切除时,以良好的新声带为特征的括约肌恢复预后优于垂直平面(真声带 + 喉室 + 假声带)结构切除的手术,后者的瘢痕通常不足以重建令人满意的括约肌;声带粘连在所有类型的手术中都不常见,在双侧手术中更频繁。这并非导致发音困难加重的具体原因,不过,除少数情况外,它在限制声门开口和促进发声方面可起到重要作用;关于功能代偿,观察结果表明,喉部能够适应解剖损伤,整个器官都参与减少气腔以形成或多或少有效的发声括约肌,各部分以其自身方式发挥作用。在最值得注意的功能代偿机制中,我们发现了声带 - 新声带、假声带处的声门机制以及杓 - 杓状软骨代偿。发声方式与新声带形态之间没有直接关系,因为并非所有新声带满意的病例都实际采用声门发声。虽然柳原发音困难频谱分类法无法区分严重发音困难和失音,但它可应用于声带切除术后有限的嗓音功能损害的客观分类。事实上,频谱分析能够证明:II型发音困难——轻度——不常见,仅在2例新声带良好且气 - 声图像完美的病例中发现;II型发音困难——中度——最常出现在黏膜下声带切除术以及其他有足够瘢痕形成的单侧切除病例中;IV型发音困难实际上对应于最重要的类型。它存在于所有类型的声带切除术中,在那些伴有严重内收肌缺陷且声门上功能代偿不足或不均衡的病例中最为普遍。

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引用本文的文献

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Lasers Med Sci. 2018 Jan;33(1):141-147. doi: 10.1007/s10103-017-2361-0. Epub 2017 Oct 26.
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Treatment with laser CO2 cordectomy and clinical implications in management of mild and moderate laryngeal precancerosis.二氧化碳激光声带切除术治疗及对轻度和中度喉癌前病变管理的临床意义。
Eur Arch Otorhinolaryngol. 2008 Feb;265(2):189-93. doi: 10.1007/s00405-007-0480-0. Epub 2007 Oct 26.