Suppr超能文献

大蒜抗菌活性的特征(作者译)

[The characteristics of the antibacterial activity of garlic (author's transl)].

作者信息

Uchida Y, Takahashi T, Sato N

出版信息

Jpn J Antibiot. 1975 Aug;28(4):638-42.

PMID:1099271
Abstract

It has been found by Cavallito (1944) that garlic (Allium sativum L.) has a strong antibacterial activity and the active principle of garlic is named "Allicin" and it has been confirmed by Stoll et al. (1948) that the allicin is derived from the alliin-alliinase system. Nevertheless, one worker in Japan (1951) stands on another view point which the effective component of garlic is some sugar-proteim because he could not find alliin in the native garlic. We intend to make sure that the alliin is contained in the native garlic, by using Hitachi Amino acid Analyser with Fraction Collecter and compared with garlic of other countrys' production. As the result of examinations, we found that the good amounts of alliin is contained in the native garlic also. The contents of alliin in garlic is varied by the species, the cultivation mode, and the district of production. The form of alliin in the tissue is a free style, and thereupon it is easy to change its chemical conformation by the method of extraction. We compared the relative capacity between 1 allicin unit by Klein (1954) and 1 cup unit by Schmidt et al. (1947). Furthermore we tested the antibiotic spectrum, using the pure crystallized alliin with the sufficient amount of raw alliinase gained by the isoelectric point precipitation and checked upon wide spectrum for Mycobacterium tuberculosis, Gram-positive and negative bacteria, and some fungi.

摘要

卡瓦利托(1944年)发现大蒜(葱属植物大蒜)具有很强的抗菌活性,大蒜的活性成分被命名为“蒜素”,斯托尔等人(1948年)证实蒜素源自蒜氨酸-蒜氨酸酶系统。然而,一位日本研究人员(1951年)持有另一种观点,即大蒜的有效成分是某种糖蛋白,因为他在本地大蒜中未发现蒜氨酸。我们打算通过使用配备馏分收集器的日立氨基酸分析仪来确定本地大蒜中是否含有蒜氨酸,并与其他国家生产的大蒜进行比较。作为检测结果,我们发现本地大蒜中也含有大量蒜氨酸。大蒜中蒜氨酸的含量因品种、种植方式和产地而异。蒜氨酸在组织中的形式是游离态,因此通过提取方法很容易改变其化学构象。我们比较了克莱因(1954年)的1个蒜素单位和施密特等人(1947年)的1个杯单位之间的相对容量。此外,我们使用通过等电点沉淀获得的足量粗蒜氨酸酶与纯结晶蒜氨酸测试了抗菌谱,并检查了对结核分枝杆菌、革兰氏阳性和阴性细菌以及一些真菌的广谱抗菌性。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验