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[氨对猪呼吸系统的影响。剂量反应关系研究]

[Effect of ammonia on the pig respiratory system. Study of the dose-response relation].

作者信息

Gustin P

机构信息

Service de Pharmacologie-Pharmacothérapie-Toxicologie, Faculté de médecine vétérinaire de l'Université de Liège.

出版信息

Bull Mem Acad R Med Belg. 1999;154(6 Pt 2):371-5.

Abstract

The effects of ammonia on the respiratory system and somatic growth have been measured in piglets taking into account the interactions with endotoxins from gram-bacteria and dust. Dose-response curves were constructed for the inflammatory reactions induced in nasal cavities, the smooth muscle hyperresponsiveness in the trachea, the permeability of alveolo-capillary barrier, the pulmonary vasomotricity, the cough reflex and the systemic effects. An acceptable level of pollution was proposed.

摘要

已在仔猪中测量了氨对呼吸系统和躯体生长的影响,并考虑了与革兰氏细菌内毒素和粉尘的相互作用。构建了鼻腔炎症反应、气管平滑肌高反应性、肺泡-毛细血管屏障通透性、肺血管舒缩性、咳嗽反射及全身效应的剂量-反应曲线。提出了可接受的污染水平。

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