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日本西部肺癌研究组临床研究的创新性益处与困难

Originality benefit and difficulty of clinical research in the West Japan Lung Cancer Group.

作者信息

Kawahara M, Ariyoshi Y, Fukuoka M, Furuse K

机构信息

Department of Medicine, National Kinki Central Hospital for Chest Diseases, Nagasone, Sakai, 591-8555, Osaka, Japan.

出版信息

Crit Rev Oncol Hematol. 2000 Oct;36(1):9-12. doi: 10.1016/s1040-8428(00)00094-9.

DOI:10.1016/s1040-8428(00)00094-9
PMID:10996519
Abstract

The West Japan Lung Cancer Study Group (recently renamed the West Japan Thoracic Oncology Group) is a non-government, non-profit regional scientific organization whose objectives are to conduct clinical research and treatment of lung cancer, and to promote lung cancer expertise among thoracic physicians and radiologists in west Japan. Since 1990, a total of 46 institutes have joined and established the rules of a society. Our major interests are phase II and III trials of chemotherapy in lung cancer. We also have participated in activities with the Japan Clinical Oncology Group (JCOG), which is supported by the National Cancer Center in Tokyo. Additionally, we have conducted phase II and III trials with the support of Japanese pharmaceutical companies. This support allows us to conduct reliable, large-scale randomized trials. Our organization's main problems are unrefined data management and few qualified statisticians, due in part to a lack of funding.

摘要

日本西部肺癌研究组(最近更名为日本西部胸部肿瘤学组)是一个非政府、非营利性的地区性科学组织,其目标是开展肺癌的临床研究和治疗,并在日本西部的胸科医生和放射科医生中推广肺癌专业知识。自1990年以来,共有46家机构加入并制定了协会规则。我们主要关注肺癌化疗的II期和III期试验。我们还参与了由东京国家癌症中心支持的日本临床肿瘤学会(JCOG)的活动。此外,我们在日本制药公司的支持下进行了II期和III期试验。这种支持使我们能够进行可靠的大规模随机试验。我们组织的主要问题是数据管理不完善,合格的统计学家很少,部分原因是资金不足。

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