Wolfe G I, Brower R D, Burns D K
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75235-8897, USA.
Neuromuscul Disord. 2000 Oct;10(7):503-6. doi: 10.1016/s0960-8966(00)00116-4.
We describe a patient who as a teenager developed a sensory-motor polyneuropathy with optic atrophy. Over the next three decades, multiple cranial neuropathies appeared. Striking areas of subperineurial cellular proliferation were observed on sural nerve biopsy. The ultrastructural and immunohistochemical characteristics of these aggregates were those of perineurial cell hyperplasia. To our knowledge, this is the second full report associating perineurial cell hyperplasia with a sensory-motor polyneuropathy and the first in the English literature.
我们描述了一名青少年患者，其患有伴有视神经萎缩的感觉运动性多神经病。在接下来的三十年里，出现了多种颅神经病变。腓肠神经活检发现显著的神经束膜下细胞增殖区域。这些聚集物的超微结构和免疫组化特征显示为神经束膜细胞增生。据我们所知，这是第二篇将神经束膜细胞增生与感觉运动性多神经病相关联的完整报告，也是英文文献中的首例报告。
