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[用转移因子致敏的大鼠淋巴结和脾脏的免疫形态学变化]

[Immunomorphological changes in the lymph nodes and spleen of rats sensitized with the transfer factor].

作者信息

Chivinda Eduardo A B, Kalynovs'ka I H

机构信息

National Agrarian University, Kiev.

出版信息

Fiziol Zh (1994). 2000;46(4):66-70.

PMID:10997302
Abstract

Changes in the rats' metatarsal pad and lymphoid organs were studied during the dermal test performing. It had been found that the dermal reaction to the antigen injection develops in the delayed hypersensitivity type. The histological changes in the examined rats' metatarsal pad correlate with changes in the popliteal lymph nodes' cell population. The lymphoblasts' number increase in the examined rats' spleen evidence the Transfer factor stimulation of the lymphocytopoiesis and plasmocytes number increase evidence the stimulation of the humoral immunity factors.

摘要

在进行皮肤试验期间,研究了大鼠跖垫和淋巴器官的变化。已发现,对抗原注射的皮肤反应呈迟发型超敏反应类型发展。所检查大鼠跖垫的组织学变化与腘淋巴结细胞群的变化相关。所检查大鼠脾脏中淋巴母细胞数量的增加证明了转移因子对淋巴细胞生成的刺激,而浆细胞数量的增加证明了体液免疫因子的刺激。

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