A new molecular approach to investigate origin and formation of structural chromosome aberrations.

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作者信息

Röthlisberger B, Schinzel A, Kotzot D

机构信息

Institute of Medical Genetics, University of Zürich, Switzerland.

出版信息

Chromosome Res. 2000;8(5):451-3. doi: 10.1023/a:1009239009599.

DOI:10.1023/a:1009239009599

PMID:10997786

Abstract

摘要

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A new molecular approach to investigate origin and formation of structural chromosome aberrations.

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Multiple mutation analyses in single tumor cells with improved whole genome amplification.利用改进的全基因组扩增技术对单个肿瘤细胞进行多重突变分析。

Am J Pathol. 1999 Jan;154(1):83-95. doi: 10.1016/S0002-9440(10)65254-6.

Molecular analysis of mosaicism for two different de novo acrocentric rearrangements demonstrates diversity in Robertsonian translocation formation.对两种不同的新发近端着丝粒重排的嵌合体进行分子分析，揭示了罗伯逊易位形成的多样性。

Am J Med Genet. 1998 Nov 16;80(3):252-9. doi: 10.1002/(sici)1096-8628(19981116)80:3<252::aid-ajmg14>3.0.co;2-q.

Genetic analysis by chromosome sorting and painting: phylogenetic and diagnostic applications.通过染色体分选和染色进行基因分析：系统发育及诊断应用

Eur J Hum Genet. 1997 Sep-Oct;5(5):253-65.

Nonhomologous Robertsonian translocations form predominantly during female meiosis.非同源罗伯逊易位主要在女性减数分裂过程中形成。

Nat Genet. 1997 Mar;15(3):231-2. doi: 10.1038/ng0397-231.

Am J Hum Genet. 1990 Dec;47(6):968-72.

A molecular genetic approach to the identification of isochromosomes of chromosome 21.

Hum Genet. 1991 Feb;86(4):375-82. doi: 10.1007/BF00201838.

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