Michie C, Kinsler V, Tulloh R, Davidson S
Department of Paediatrics, Ealing Hospital NHS Trust, Uxbridge Road, London UB1 3HW, UK.
Arch Dis Child. 2000 Oct;83(4):353-5. doi: 10.1136/adc.83.4.353.
Long term follow up of 259 cases of Kawasaki disease led to the observation that 11% of children have episodes of recurrent peeling of the skin for several years after their recovery. These events were usually associated with an upper respiratory tract infection and were distinct from a recurrence of Kawasaki disease. Repeeling was significantly less frequent in children who had suffered coronary artery dilatation and was more frequently seen in those with nasal staphylococcal colonisation. The mechanism for this phenomenon is unclear, but it has been observed in a number of other conditions caused by infectious agents and their toxins. Paediatricians need to be aware of this phenomenon which is distinct from recurrence of Kawasaki disease.
对259例川崎病患儿进行长期随访后发现,11%的患儿在康复后的数年中出现反复皮肤脱皮现象。这些情况通常与上呼吸道感染有关,且与川崎病复发不同。曾发生冠状动脉扩张的患儿反复脱皮的频率明显较低,而鼻腔有葡萄球菌定植的患儿则更常出现反复脱皮。这种现象的机制尚不清楚,但在由感染因子及其毒素引起的许多其他病症中也观察到了这种情况。儿科医生需要了解这种与川崎病复发不同的现象。