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冠状动脉造影:适应证与陷阱

Coronary arteriography: indications and pitfalls.

作者信息

Friesinger G C, Perry J M

出版信息

Cardiovasc Clin. 1975;6(3):265-81.

PMID:1100239
Abstract

Selective coronary arteriography has become an unusually useful technique in evaluating patients with known or suspected ischemic heart disease. The contribution of F. Mason Sones in developing the technique and in emphasizing that properly performed studies in experienced hands can be done at an acceptable risk cannot be overemphasized. Although the study can give information only on the anatomical aspects of the disease, it has remarkably broadened ouo understanding of the whole spectrum of coronary arteriosclerosis and ischemic heart disease. This is related to the fact that the method has provided the opportunity to study an extraordinarily large number of patients representing virtually every clinical subset of the disease. The importance of nonanatomical factors, better prognostic information about the disease, and more complete understanding of the hemodynamic ocrrelates and mechanisms of drug action have resulted from investigative studies using coronary arteriographic methods. Because ischemic heart disease is such a complex and variable entity, it is important to stress that coronary arteriography and left ventricular angiography can provide only anatomical information, and that the method has significant but ordinarily recognizable limitations. Some of these limitations are technical and are not important considerations in experienced hands in well-run laboratories. Other problems are inherent in the anatomical complexity of the disease and the coronary circulation. Hence, appropriate emphasis on the details of the patient's history, including risk factors and age, as well as other selected clinical laboratory studiies, such as exercise electrocardiography, are important in assessing the patient's total problem. Because of these factors, the greatest value of coronary arteriography is realized when it is performed as part of a thoughtful, detailed--and highly individualized--evaluation of the patient.

摘要

选择性冠状动脉造影已成为评估已知或疑似缺血性心脏病患者的一项极其有用的技术。F. 梅森·索恩斯在这项技术的开发过程中发挥了重要作用,并且强调在经验丰富的医生手中正确操作该检查,其风险是可以接受的,这一点无论怎样强调都不为过。尽管这项检查只能提供疾病的解剖学方面的信息,但它极大地拓宽了我们对冠状动脉粥样硬化和缺血性心脏病整个范畴的理解。这与该方法为研究大量几乎涵盖该病每个临床亚组的患者提供了机会这一事实有关。使用冠状动脉造影方法进行的研究已经揭示了非解剖学因素的重要性、关于该疾病更好的预后信息以及对血流动力学相关性和药物作用机制更全面的理解。由于缺血性心脏病是一个如此复杂和多变的实体,必须强调冠状动脉造影和左心室造影只能提供解剖学信息,并且该方法存在显著但通常可识别的局限性。其中一些局限性是技术性的,在设备良好的实验室中,经验丰富的医生进行操作时并非重要的考虑因素。其他问题则源于该疾病和冠状动脉循环的解剖复杂性。因此,在评估患者的整体病情时,适当重视患者病史的细节,包括危险因素和年龄,以及其他选定的临床实验室检查,如运动心电图,是很重要的。由于这些因素,当冠状动脉造影作为对患者进行全面、细致且高度个性化评估的一部分时,其最大价值才能得以体现。

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