Gloor M, Brümmer W, Friederich H C
Hautarzt. 1975 Jun;26(6):309-11.
In animal experiments with 12 male guinea pigs skin defects have been covered with one-sided bridge flaps. As opposed to corresponding earlier investigations on free full thickness skin autografts no irreversible and much less reversible damage to the hair follicles could be demonstrated in these skin flaps in the primary postoperative phase. In the later postoperative phase, there was--similar to the free full thickness skin autografts--a synchronization of hair change over several cycles, but on the other hand there was no precipitation of hair change. As a result of these findings it may be assumed that the secondary damage to the hair follicles in the later postoperative phase is not as pronounced in these flaps as in free full thickness skin autografts.
在对12只雄性豚鼠进行的动物实验中,皮肤缺损处用单侧桥形皮瓣覆盖。与早期关于游离全厚皮片自体移植的相应研究相反,在术后初期,这些皮瓣中未发现毛囊有不可逆损伤,可逆性损伤也少得多。在术后后期,与游离全厚皮片自体移植类似,毛发变化在几个周期内同步,但另一方面,毛发变化没有提前。基于这些发现,可以推测,在术后后期,这些皮瓣中毛囊的继发性损伤不如游离全厚皮片自体移植中明显。