Ortiz H, Azpeitia D, Casalots J, Sitges A
J Chir (Paris). 1975 May-Jun;109(5-6):691-6.
The authors carried out 88 sutures of the ascending colon in Wistar rats, 44 in inversion and the remainder in eversion. The suture material used was monofilament 9/0 nylon. The intestinal diameter was measured using an instrument and the healing process studied by means of the following parameters: granulocytes, oedema, fibrin, fibroblasts and re-epithelialisation of the mucosa, on histology. The results prove that inverted sutures heal within 10 days, whereas everted sutures are not healed after 17 days. Furthermore, we demonstrated the fact that, after 72 hours, the intestinal caliber above the suture showed no appreciable differences compared with that of the normal colon.
作者在Wistar大鼠身上进行了88例升结肠缝合术，其中44例采用内翻缝合，其余采用外翻缝合。所用缝合材料为单丝9/0尼龙线。使用仪器测量肠直径，并通过以下组织学参数研究愈合过程：粒细胞、水肿、纤维蛋白、成纤维细胞和黏膜再上皮化。结果证明，内翻缝合在10天内愈合，而外翻缝合在17天后仍未愈合。此外，我们还证明了，72小时后，缝合处上方的肠管径与正常结肠相比没有明显差异。
