同种异体移植排斥反应中的趋化因子及其受体
Chemokines and their receptors in allograft rejection.
作者信息
Hancock W W, Gao W, Faia K L, Csizmadia V
机构信息
Millennium Pharmaceuticals Incorparated, Cambridge, MA 02139, USA.
出版信息
Curr Opin Immunol. 2000 Oct;12(5):511-6. doi: 10.1016/s0952-7915(00)00130-8.
Abstract
Despite current recognition of over 40 chemokines and more than 18 chemokine receptors, understanding of their role in transplant immunobiology and transplant rejection is extremely limited and fragmentary. Recent literature has demonstrated the presence of chemokines and their receptors in transplants and some studies demonstrate important functional roles.
摘要
尽管目前已识别出40多种趋化因子和18种以上的趋化因子受体，但对它们在移植免疫生物学和移植排斥反应中的作用的了解极为有限且支离破碎。最近的文献表明移植中存在趋化因子及其受体，一些研究也证明了它们的重要功能作用。
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