Hoyle G, Barker D L
J Exp Zool. 1975 Sep;193(3):433-9. doi: 10.1002/jez.1401930322.
Dorsal unpaired median (DUM) neurons of locusts and grasshoppers inhibit the instrinsic rhythm of contraction of metathoracic extensor tibia muscle fibers. This physiological action is mimicked by very low concentrations of octopamine and by higher concentrations of dopamine and noradrenaline. We have examined the synthesis of biogenic amines from tritiated tyrosine by these neurons. DUM cell bodies and a peripheral nerve containing the DUM axon which terminates in the extensor tibia both produced octopamine, but neither noradrenaline nor dopamine synthesis was detected. The observations support the suggestion that the dorsal unpaired median neurons are octopaminergic.
蝗虫和蚱蜢的背侧不成对中间神经元（DUM）会抑制后胸伸胫肌纤维的内在收缩节律。极低浓度的章鱼胺以及较高浓度的多巴胺和去甲肾上腺素都能模拟这种生理作用。我们研究了这些神经元从氚化酪氨酸合成生物胺的情况。DUM细胞体以及一条包含终止于伸胫肌的DUM轴突的外周神经都产生了章鱼胺，但未检测到去甲肾上腺素和多巴胺的合成。这些观察结果支持了背侧不成对中间神经元是章鱼胺能神经元这一观点。
