Shaw M J, Kumar N D, Duggal M, Fiske J, Lewis D A, Kinsella T, Nisbet T
Restorative Dentistry, Birmingham Dental Hospital, Birmingham, UK.
Br J Oral Maxillofac Surg. 2000 Oct;38(5):519-24. doi: 10.1054/bjom.2000.0468.
Many tumours of the head and neck are treated by clinical oncologists using radiotherapy. This treatment modality is particularly effective in destroying rapidly dividing cells, hence its value in cancer treatment. The tissues of the oral mucosa, the salivary glands and blood vessels can be damaged as the result of radiotherapy treatment. As a result, patients experience unwanted oral effects that have both short and long-term implications. The outlook following treatment for head and neck cancer continues to improve and, as people keep their teeth into later life, dentists will increasingly be expected to address the oral problems that patients experience after radiotherapy. The aim of this article is to review the current literature concerning the implications and management of these oral implications of cancer treatment.
许多头颈肿瘤由临床肿瘤学家采用放射疗法进行治疗。这种治疗方式在破坏快速分裂的细胞方面特别有效,因此在癌症治疗中具有重要价值。放射治疗可能会导致口腔黏膜、唾液腺和血管组织受损。结果,患者会出现一些不良的口腔反应,这些反应具有短期和长期的影响。头颈癌治疗后的前景持续改善,并且随着人们保留牙齿的时间延长至晚年,预计牙医将越来越多地处理患者放疗后出现的口腔问题。本文的目的是综述当前有关癌症治疗这些口腔影响的相关情况及处理方法的文献。