Bouin M, Savoye G, Maillot C, Hellot M F, Guédon C, Denis P, Ducrotté P
Digestive Tract Research Group, Rouen University Hospital, Rouen, France.
Am J Clin Nutr. 2000 Oct;72(4):1040-6. doi: 10.1093/ajcn/72.4.1040.
Fiber supplementation during enteral nutrition has been recommended, but the effect of soluble compared with insoluble fiber supplements on antroduodenal motility is unknown.
The objective of this study was to compare antroduodenal motor patterns in 8 healthy volunteers during and after gastric infusion of 3 different diets: a fiber-free diet, an insoluble-fiber diet, and a mixed-fiber diet (50% soluble fiber and 50% insoluble fiber).
Manometric studies with the 3 different diets (2100 kJ) were performed in random order. Antroduodenal motility was monitored continuously for 6 h by using a pneumohydraulic system to calculate the number, amplitude, and duration of the pressure waves; the area under the curve (AUC); and the percentage of time occupied by motor activity before, during, and after each type of infusion. Variations in antral areas were measured by ultrasonography.
The gastric motor response was significantly higher, whatever the diet, in the distal antral recording site than in the 2 more proximal sites. In the proximal but not the distal antrum, the number of waves, the AUC, and the percentage of time occupied by motor activity were higher (P: < 0.04) with the mixed-fiber than with the insoluble-fiber diet. No significant differences in variations of antral area were observed among the 3 diets. In the duodenum, motor variables were not significantly different among the 3 diets.
A gastric infusion induced a greater motor response in the distal than in the proximal antrum. A mixed-fiber diet was associated with significantly greater proximal antral motility than was an insoluble-fiber diet. There was no significant difference among the 3 formulas in duodenal motor variables or in variations in antral area as measured by ultrasound.
肠内营养期间推荐补充膳食纤维，但可溶性膳食纤维补充剂与不可溶性膳食纤维补充剂对胃十二指肠动力的影响尚不清楚。
本研究的目的是比较8名健康志愿者在胃内输注三种不同饮食期间及之后的胃十二指肠运动模式：无纤维饮食、不可溶性纤维饮食和混合纤维饮食（50%可溶性纤维和50%不可溶性纤维）。
对三种不同饮食（2100千焦）进行随机顺序的测压研究。使用气动液压系统连续监测胃十二指肠动力6小时，以计算压力波的数量、幅度和持续时间；曲线下面积（AUC）；以及每种输注类型之前、期间和之后运动活动所占时间的百分比。通过超声测量胃窦面积的变化。
无论饮食如何，胃窦远端记录部位的胃动力反应均显著高于近端的另外两个部位。在胃窦近端而非远端，混合纤维饮食组的波数、AUC和运动活动所占时间百分比均高于不可溶性纤维饮食组（P<0.04）。三种饮食之间胃窦面积变化无显著差异。在十二指肠，三种饮食之间的运动变量无显著差异。
胃内输注引起胃窦远端的动力反应大于近端。与不可溶性纤维饮食相比，混合纤维饮食与胃窦近端动力显著增强有关。三种配方在十二指肠运动变量或超声测量的胃窦面积变化方面无显著差异。
