Cappellani A, Zanghì A, Di Vita M, Zanghì G, Tomarchio G, Petrillo G
Dipartimento di Chirurgia, Università di Catania.
Ann Ital Chir. 2000 May-Jun;71(3):379-83.
Hemangiomas are frequent benign tumors of the liver. Symptoms (abdominal pain and fullness) are mostly seen in giant lesions. Rupture is the most severe complication, can occur spontaneously, with intraperitoneal bleeding, in 1-4% of hemangiomas and has been described in about 30 cases in the international literature with a high mortality (about 60%). This complication is the principal indication for surgery. Although spiral CAT scan and MR are actually the most efficacious imaging methods for study of liver hemangiomas, after Echography, emergency techniques that allows a simultaneous therapeutic approach--as is angiography--are preferable. Trans-arterial embolization (TAE) is in fact useful to stop bleeding and then to perform a safer surgery. A successful embolization can delay the surgical resection of the hemangioma for the time necessary to recover from the hemodynamic distress. Aside from the success of angiographic approach, surgery remains mandatory, effective in stopping the bleeding and in preventing re-bleeding or other complications of TAE such as abscess, fever, etc.. Intraoperative echography currently is the best method to identify vasculo- biliary anatomy and to perform a correct resection. The absence of risk factors for spontaneous rupture of liver hemangiomas, makes this event unpredictable. The best treatment for non-ruptured hemangiomas is still controversial but surgery is usually limited to symptomatic tumors larger than 10 cm.
肝血管瘤是常见的肝脏良性肿瘤。症状(腹痛和腹胀)多见于巨大病变。破裂是最严重的并发症,可自发发生,导致腹腔内出血,在1% - 4%的肝血管瘤中会出现,国际文献中约有30例相关报道,死亡率较高(约60%)。这种并发症是手术的主要指征。尽管螺旋CT扫描和磁共振成像实际上是研究肝血管瘤最有效的影像学方法,但在超声检查之后,像血管造影这样能同时进行治疗的急诊技术更可取。经动脉栓塞术(TAE)实际上有助于止血,进而进行更安全的手术。成功的栓塞可以将肝血管瘤的手术切除推迟到从血流动力学窘迫中恢复所需的时间。除了血管造影方法的成功之外,手术仍然是必要的,它能有效止血并预防TAE的再出血或其他并发症,如脓肿、发热等。术中超声检查目前是识别血管 - 胆管解剖结构并进行正确切除的最佳方法。肝血管瘤自发破裂不存在危险因素,使得这一事件无法预测。对于未破裂的肝血管瘤,最佳治疗方法仍存在争议,但手术通常限于直径大于10 cm的有症状肿瘤。