来自毛叶榄仁的二氢黄酮醇。

Dihydroflavonols from Lannea coromandelica.

作者信息

Islam M T, Tahara S

机构信息

Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University, Sapporo, Japan.

出版信息

Phytochemistry. 2000 Aug;54(8):901-7. doi: 10.1016/s0031-9422(00)00048-0.

DOI:10.1016/s0031-9422(00)00048-0

PMID:11014286

Abstract

The dihydroflavonols, (2R,3S)-(+)-3',5-dihydroxy-4',7-dimethoxydihydroflavonol and (2R,3R)-(+)-4',5,7-trimethoxydihydroflavonol were isolated from the stem bark of Lannea coromandelica, along with the known (2R,3R)-(+)-4',7-di-O-methyldihydroquercetin, (2R,3R)-(+)-4',7-di-O-methyldihydrokaempferol and (2R,3R)-(+)-4'-O-methyldihydroquercetin. All five compounds were isolated for the first time from the genus Lannea; furthermore, (2R,3S)-(+)-3',5-dihydroxy-4',7-dimethoxydihydroflavonol, was a rare cis-type isomer. The structures of all compounds were elucidated by spectroscopic methods including 2D NMR and CD analysis.

摘要

从柯氏榄仁树的茎皮中分离出二氢黄酮醇、(2R,3S)-(+)-3',5-二羟基-4',7-二甲氧基二氢黄酮醇和(2R,3R)-(+)-4',5,7-三甲氧基二氢黄酮醇，以及已知的(2R,3R)-(+)-4',7-二-O-甲基二氢槲皮素、(2R,3R)-(+)-4',7-二-O-甲基二氢山奈酚和(2R,3R)-(+)-4'-O-甲基二氢槲皮素。所有这五种化合物均首次从榄仁树属中分离得到；此外，(2R,3S)-(+)-3',5-二羟基-4',7-二甲氧基二氢黄酮醇是一种罕见的顺式异构体。所有化合物的结构均通过包括二维核磁共振和圆二色分析在内的光谱方法进行了阐明。