Caro J F, Israel H L, Glennon J A
Am J Med Sci. 1979 May-Jun;277(3):289-94.
Five of 300 women with sarcoidosis had galactorrhea. Basal prolactin levels were mildly but significantly elevated when compared to controls and sarcoidosis patients without galactorrhea. Prolactin levels responded to thyrotropin releasing hormone and L-dopa administration, but not chlorpromazine. Luteinizing hormone and follicle-stimulating hormone concentrations responded normally to luteinizing hormone-releasing hormone in all sarcoidosis patients studied, as did growth hormone to insulin hypoglycemia. These results indicate that galactorrhea in sarcoidosis is an uncommon phenomenon, probably due to hypothalamic dysfunction and associated with mildly elevated prolactin levels.
300例结节病女性患者中有5例出现溢乳。与对照组及无溢乳的结节病患者相比，基础催乳素水平轻度但显著升高。催乳素水平对促甲状腺激素释放激素和左旋多巴给药有反应，但对氯丙嗪无反应。在所有研究的结节病患者中，促黄体生成素和促卵泡激素浓度对促黄体生成素释放激素反应正常，生长激素对胰岛素低血糖反应也正常。这些结果表明，结节病中的溢乳是一种罕见现象，可能是由于下丘脑功能障碍，且与催乳素水平轻度升高有关。
