Piccione W
Department of Cardiovascular-Thoracic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA.
J Heart Lung Transplant. 2000 Aug;19(8 Suppl):S89-94. doi: 10.1016/s1053-2498(99)00110-2.
Long-term implanted left ventricular assist devices (LVADs) have significantly improved the care of patients awaiting heart transplantation and will provide an alternative therapy to select patients with heart failure. However, although the technology and clinical results continue to improve, LVAD implantation is still associated with a significant level of complications. Left ventricular assist device-associated complications can be broadly divided by their temporal occurrence. Early complications include perioperative hemorrhage, air embolism, and right ventricular failure. Beyond the perioperative period, late complications consist primarily of infection, thromboembolism, and primary device failure. An improved understanding of the mechanisms involved should aid the clinician in further reducing the incidence of these occurrences.
长期植入式左心室辅助装置（LVADs）显著改善了等待心脏移植患者的护理，并将为选定的心力衰竭患者提供替代治疗。然而，尽管该技术和临床结果不断改善，但LVAD植入仍伴有显著程度的并发症。左心室辅助装置相关并发症可根据其发生时间大致分类。早期并发症包括围手术期出血、空气栓塞和右心室衰竭。在围手术期之后，晚期并发症主要包括感染、血栓栓塞和原发性装置故障。更好地理解其中涉及的机制应有助于临床医生进一步降低这些情况的发生率。
