Campbell A E
Department of Microbiology and Molecular Cell Biology, Eastern Virginia School, Norfolk, Virginia 23507, USA.
Viral Immunol. 2000;13(3):269-72. doi: 10.1089/08828240050144608.
The Keystone Symposium on Cell Biology of Virus Entry, Replication, and Pathogenesis held in Taos, New Mexico February 29 to March 5, 2000 to a large degree fulfilled its purpose to facilitate interdisciplinary exchange of information. The Keynote Address by Sir John J. Skehel (National Institute for Medical Research, London) initiated discussion on the antigenic analyses of influenza virus hemagglutinins. Subsequent topics covered the earliest events in viral receptor-mediated entry through membrane fusion to virus assembly, genetics, pathogenesis, and immunology. While a significant number of taxonomically different viruses was discussed, several common themes emerged from plenary sessions and poster workshops. A few selected topics are highlighted below.
2000年2月29日至3月5日在新墨西哥州陶斯举行的病毒进入、复制与发病机制细胞生物学研讨会在很大程度上实现了促进跨学科信息交流的目的。约翰·J·斯凯尔爵士(伦敦国家医学研究所)的主题演讲开启了关于流感病毒血凝素抗原分析的讨论。随后的主题涵盖了从病毒受体介导的通过膜融合进入细胞的最早事件到病毒组装、遗传学、发病机制和免疫学。虽然讨论了大量分类学上不同的病毒,但全体会议和海报研讨会出现了几个共同主题。以下突出介绍一些选定的主题。