Tareev E M, Serov V V
Arkh Patol. 1975;37(7):3-11.
In studies of the Bright disease the most promising have proved to be functional-physiological and immunological lines, genetic, morphological and enzymological investigations. Achievements of nephrology in studies of nosological forms have made it possible to describe new disorders, to give different interpretation of the diseases existed earlier, and to fractionate the "monolith" nosological forms, which complicates the development of classificational forms of kidney diseases. Singling out of individual disease is impeded, moreover, by the pathomorphosis of kidney diseases, a phenomenon particularly noticeable during the last decade, which not infrequently is difficult to be distinguished from pathology of therapy. The existing classifications of kidney diseases do not meet any longer theoretical and practical needs of current nephrology. In elaborating rational classificational schemes one should be guided not by one but by several principles, including etiological, pathogenetic, clinical, and structural ones, hereditary pathology being considered quite separately.
在对Bright病的研究中，最有前景的已被证明是功能生理学和免疫学研究方向、遗传学、形态学及酶学研究。肾脏病学在疾病分类形式研究方面所取得的成果，使得描述新的病症、对以往存在的疾病给出不同的解释以及对“整体”的疾病分类形式进行细分成为可能，而这又使肾脏病分类形式的发展变得复杂。此外，肾脏病的病理形态变化也阻碍了对个别疾病的区分，这一现象在过去十年尤为明显，而且常常难以与治疗病理相区分。现有的肾脏病分类已不再满足当前肾脏病学的理论和实际需求。在制定合理的分类方案时，不应仅依据某一条原则，而应依据若干原则，包括病因学、发病机制、临床及结构等方面的原则，遗传性病理学则应单独予以考虑。
