Weld K J, Graney M J, Dmochowski R R
Department ofUrology, University of Tennessee-Memphis, Memphis, Tennessee, USA.
Urology. 2000 Oct 1;56(4):565-8. doi: 10.1016/s0090-4295(00)00761-5.
To investigate the significance of categorizing detrusor sphincter dyssynergia (DSD) by type in patients with chronic spinal cord injury.
A retrospective review of the charts, video-urodynamic studies, and upper tract radiographic studies of 269 patients with post-traumatic, suprasacral spinal cord injuries was performed. The patients were categorized according to the DSD type (intermittent or continuous), level and completeness of injury, intravesical pressure at leak, upper tract complications, and interval since injury.
Of the 269 patients, 20 (7.4%), 216 (80.3%), and 33 (12.3%) had no DSD, intermittent DSD, and continuous DSD, respectively. No significant association between the specific level of injury and the DSD type was found (P = 0.71). The presence of DSD was associated with complete injuries, elevated intravesical pressures, and upper tract complications (P <0.01); these associations were more prominent with continuous DSD than with intermittent DSD. The proportion of patients with no DSD, intermittent DSD, and continuous DSD was unchanged during the chronic follow-up period.
The clinical significance of DSD type is not crucial, since patients with both intermittent and continuous DSD require urodynamic surveillance and expedient treatment to minimize urologic complications. However, the presence of continuous DSD is one of several factors that may require earlier urodynamic follow-up.
探讨按类型对慢性脊髓损伤患者逼尿肌括约肌协同失调(DSD)进行分类的意义。
对269例创伤后骶上脊髓损伤患者的病历、视频尿动力学研究及上尿路影像学研究进行回顾性分析。根据DSD类型(间歇性或持续性)、损伤平面和完整性、漏尿时膀胱内压、上尿路并发症及伤后间隔时间对患者进行分类。
269例患者中,分别有20例(7.4%)无DSD、216例(80.3%)有间歇性DSD、33例(12.3%)有持续性DSD。未发现损伤的具体平面与DSD类型之间存在显著关联(P = 0.71)。DSD的存在与完全性损伤、膀胱内压升高及上尿路并发症相关(P <0.01);这些关联在持续性DSD患者中比在间歇性DSD患者中更显著。在慢性随访期间,无DSD、间歇性DSD和持续性DSD患者的比例未发生变化。
DSD类型的临床意义并不关键,因为间歇性和持续性DSD患者均需要尿动力学监测及及时治疗,以尽量减少泌尿系统并发症。然而,持续性DSD的存在是可能需要更早进行尿动力学随访的因素之一。