Piovesan E J, Tatsui C E, Kowacs P A, Prazeres R F, Lange M C, Antoniuk S A, Werneck L C
Departamento de Clínica Médica, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, 80069-900, Brasil.
Arq Neuropsiquiatr. 2000 Sep;58(3B):947-51. doi: 10.1590/s0004-282x2000000500027.
Despite the lipomas are the tumors that more commonly occur in the corpus callosum (CC), its incidence in the population is not common. We report on a 5-year old boy, with history of retardation in the psychomotor development and disturbs in the gait, secondary to generalized hypotony. Magnetic resonance imaging showed a curvilinear lipoma of the CC related to its hypertrophy. In the literature patients with CC lipoma usually have agenesis or hypotrophy of the CC, but in the reported case we have seen, by the first time, a hypertrophy of the CC. We made embryologic, genetic, clinical, radiographic and therapeutic considerations about the patients that have CC lipoma comparing to findings in the case we report.
尽管脂肪瘤是最常发生于胼胝体(CC)的肿瘤,但其在人群中的发病率并不常见。我们报告了一名5岁男孩,有精神运动发育迟缓及步态障碍病史,继发于全身性肌张力减退。磁共振成像显示CC处有一个与CC肥厚相关的曲线状脂肪瘤。文献中CC脂肪瘤患者通常有CC发育不全或发育不良,但在我们报告的病例中,首次发现了CC肥厚。我们针对患有CC脂肪瘤的患者,与我们报告病例中的发现进行比较,从胚胎学、遗传学、临床、影像学和治疗方面进行了考量。