Department of Paediatric Neurology and Metabolic Diseases, Hôpital Robert Debré, APHP, 48 Bd Sérurier, 75935, Paris Cedex 19, France.
Pediatr Radiol. 2010 Aug;40(8):1417-20. doi: 10.1007/s00247-009-1534-9. Epub 2010 Feb 12.
Intracranial lipomas are rare congenital malformations that can often be seen in association with other brain malformations; agenesis or dysgenesis of the corpus callosum is the most frequently associated brain anomaly. They are usually pericallosal asymptomatic midline lesions. Intracranial lipomas associated with a non-contiguous cerebral aneurysm are extremely rare. We report an infant with partial agenesis of the corpus callosum and pericallosal lipoma associated with cerebral haemorrhage due to a distal middle cerebral artery aneurysm. Such an association is probably not fortuitous and could suggest a pathogenic relationship.
颅内脂肪瘤是一种罕见的先天性畸形,常与其他脑畸形有关;胼胝体发育不全或发育不良是最常见的相关脑异常。它们通常是位于胼胝体周围的无症状中线病变。颅内脂肪瘤合并非连续性大脑动脉瘤极为罕见。我们报告了一例部分胼胝体发育不全和胼胝体脂肪瘤的婴儿,该婴儿因大脑中动脉远端动脉瘤导致脑出血。这种关联可能并非偶然,可能提示存在发病机制。