免疫接种。最新情况：艾滋病疫苗的研究

Immunization. Update: search for an AIDS vaccine.

作者信息

Bende S, Johnston M I

机构信息

Vaccine and Prevention Research Program, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Md., USA.

出版信息

AIDS Read. 2000 Sep;10(9):526-32, 534-8.

PMID:11019448

Abstract

Identifying a successful HIV preventive vaccine is among the highest research priorities of the US NIH. While therapies for HIV have brought hope to those who are already HIV-infected, stopping the worldwide epidemic will require safe, effective HIV vaccines. Here, we describe scientific and other obstacles to attaining that goal and provide a brief synopsis of clinical trial results, recent preclinical results, and future priorities.

摘要

确定一种成功的HIV预防性疫苗是美国国立卫生研究院（NIH）的最高研究重点之一。虽然针对HIV的疗法给已感染HIV的人带来了希望，但要阻止全球范围内的疫情，还需要安全有效的HIV疫苗。在此，我们描述了实现这一目标所面临的科学及其他障碍，并简要概述了临床试验结果、近期临床前研究结果以及未来的重点。