Burns S A
Schepens Eye Research Institute, Boston, MA 02114, USA.
J Refract Surg. 2000 Sep-Oct;16(5):S566-9. doi: 10.3928/1081-597X-20000901-15.
To investigate factors controlling the aberrations of the eye, including accommodation, wavelength, and the apodization of the optics of the eye by cone directional selectivity.
We constructed a new implementation of the Spatially Resolved Refractometer (SRR). This is an instrument, based on the Scheiner principle, that allows the rapid psychophysical measurement of the complete wavefront aberrations of the eye. We have investigated both the reproducibility of the measurements, and the effect of static accommodation and wavelength on the wavefront aberrations of the eye. In addition we combined the wave front aberrations with cone photoreceptor directionality to compute the modulation transfer function of the eye, at the retinal level.
The SRR measurements were rapid (4 minutes per measurements, 12 minutes per patient) and reproducible. There are significant changes in wavefront quality with accommodation, with optimal image quality near the resting point of accommodation. Image quality for polychromatic (white) light is strongly affected by both longitudinal and transverse chromatic aberration. Finally, we find that incorporating the effects of cone directionality into the calculation of image quality can increase image quality by up to 50%.
Calculation of a simple "optimal surgical shape" for wave-front guided refractive surgery will depend on improved understanding of the interplay between the biological and physical properties of the eye.
研究控制眼睛像差的因素，包括调节、波长以及视锥细胞方向选择性对眼睛光学系统的切趾作用。
我们构建了空间分辨折射仪（SRR）的一种新形式。这是一种基于沙伊纳原理的仪器，可对眼睛的完整波前像差进行快速心理物理学测量。我们研究了测量的可重复性，以及静态调节和波长对眼睛波前像差的影响。此外，我们将波前像差与视锥光感受器的方向性相结合，以计算视网膜水平上眼睛的调制传递函数。
SRR测量快速（每次测量4分钟，每位患者12分钟）且可重复。随着调节，波前质量有显著变化，在调节静止点附近图像质量最佳。多色（白色）光的图像质量受到纵向和横向色差的强烈影响。最后，我们发现将视锥细胞方向性的影响纳入图像质量计算可使图像质量提高多达50%。
波前引导屈光手术的简单“最佳手术形状”计算将取决于对眼睛生物学和物理特性之间相互作用的更好理解。
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